Kurz C L, Ewbank J J
Centre d'Immunologie de Marseille-Luminy, INSERM/CNRS/Université de la Méditerranée, Case 906, 13288 Marseille Cedex 9, France.
Trends Microbiol. 2000 Mar;8(3):142-4. doi: 10.1016/s0966-842x(99)01691-1.
The nematode worm Caenorhabditis elegans, for which the complete genome sequence is available, has several other advantages as an experimental system, and has already been widely used as a model for the study of vertebrate biology. Recent investigations have revealed that C. elegans could also be an extremely useful model system in the study of bacterial pathogenesis and have reinforced the notion that common virulence and host defence mechanisms exist.
秀丽隐杆线虫这种线虫的完整基因组序列已经知晓,作为一个实验系统它还有其他几个优点,并且已经被广泛用作研究脊椎动物生物学的模型。最近的研究表明,秀丽隐杆线虫在细菌致病机制研究中也可能是一个极其有用的模型系统,并且强化了存在共同毒力和宿主防御机制这一观点。