[慢性髓性白血病中的新染色体异常]
[New chromosome abnormality in chronic myeloid leukemia].
作者信息
Berger R, Gyger M
出版信息
Nouv Rev Fr Hematol (1978). 1976;16(3):309-20.
PMID:1070709
Abstract
A case of chronic myelogenous leukemia with myelofibrosis and failure to respond to busulfan therapy has been reported. An abnormal clone with a rearrangement of four chromosomes, 46, XX, t(1;9) (q21; q24), t(6;22) (q26;q11) was observed. The possible significance of these chromosome abnormalities which are different from the t(9;22) translocation in C.M.L. is discussed.
摘要
已报告一例慢性粒细胞白血病合并骨髓纤维化且对白消安治疗无反应的病例。观察到一个异常克隆，其四条染色体发生重排，核型为46, XX, t(1;9) (q21; q24), t(6;22) (q26;q11)。本文讨论了这些与慢性粒细胞白血病中t(9;22)易位不同的染色体异常的可能意义。
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