树突状细胞上的裸抗原呈递分子。

Naked antigen-presenting molecules on dendritic cells.

作者信息

Davoust J, Banchereau J

出版信息

Nat Cell Biol. 2000 Mar;2(3):E46-8. doi: 10.1038/35004075.

Abstract

Antigen-presenting cells work to present peptides derived from exogenous and endogenous antigens to circulating T cells, sparking off an immune response. Dendritic cells are unique amongst antigen-presenting cells, not least for their newly described ability to circumvent the need to internalize exogenous antigens before presenting them.

摘要

抗原呈递细胞的作用是将源自外源性和内源性抗原的肽段呈递给循环中的T细胞，从而引发免疫反应。树突状细胞在抗原呈递细胞中独具特色，尤其是它们新近被描述的一种能力，即在呈递外源性抗原之前无需将其内化。