巨细胞病毒感染可能导致输尿管坏死。
Cytomegalovirus infection may cause ureteral necrosis.
作者信息
Peretti N, Saïd M H, Bouvier R, Koch-Nogueira P C, Thouvenot D, Martin X, Cochat P
机构信息
Département de Pédiatrie, Hôpital Edouard Herriot and Université Claude Bernard, Lyon, France.
出版信息
Transplantation. 2000 Feb 27;69(4):670-1. doi: 10.1097/00007890-200002270-00034.
Cytomegalovirus (CMV) infection has protean presentation among immunocompromised patients, but the urinary tract is rarely involved. We report a case of extensive ureteral necrosis in a renal transplant, 12-year-old patient with typical histological feature of CMV inclusions. The role of CMV was confirmed by immunohistochemical analysis and concomitant CMV DNA detection in peripheral blood leukocytes by polymerase chain reaction analysis. CMV infection can, therefore, be regarded as a possible cause of ureteral necrosis in renal transplant recipients.
巨细胞病毒（CMV）感染在免疫功能低下的患者中表现多样，但很少累及泌尿道。我们报告了一例肾移植术后12岁患者发生广泛输尿管坏死的病例，其具有典型的CMV包涵体组织学特征。通过免疫组化分析以及聚合酶链反应分析检测外周血白细胞中的CMV DNA，证实了CMV的作用。因此，CMV感染可被视为肾移植受者输尿管坏死的一个可能原因。
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