Davies C W, Tasker A D, Padley S P, Davies R J, Gleeson F V
Osler Chest Unit, Churchill Hospital, Oxford, UK.
Clin Radiol. 2000 Mar;55(3):217-21. doi: 10.1053/crad.1999.0366.
To document the presence and extent of air trapping on high resolution computed tomography (HRCT) in patients with pulmonary sarcoidosis and correlate HRCT features with pulmonary function tests.
Twenty-one patients with pulmonary sarcoidosis underwent HRCT and pulmonary function assessment at presentation. Inspiratory and expiratory HRCT were assessed for the presence and extent of air trapping, ground-glass opacification, nodularity, septal thickening, bronchiectasis and parenchymal distortion. HRCT features were correlated with pulmonary function tests.
Air trapping on expiratory HRCT was present in 20/21 (95%) patients. The extent of air trapping correlated with percentage predicted residual volume (RV)/total lung capacity (TLC) (r = 0.499;P < 0.05) and percentage predicted maximal mid-expiratory flow rate between 25 and 75% of the vital capacity (r = -0.54;P < 0.05). Ground-glass opacification was present in four of 21 (19%), nodularity in 18/21 (86%), septal thickening in 18/21 (86%), traction bronchiectasis in 14/21 (67%) and distortion in 12/21 (57%) of patients; there were no significant relationships between these CT features and pulmonary function results.
Air trapping is a common feature in sarcoidosis and correlates with evidence of small airways disease on pulmonary function testing.
记录肺结节病患者高分辨率计算机断层扫描（HRCT）上空气潴留的存在情况及范围，并将HRCT特征与肺功能测试结果相关联。
21例肺结节病患者在就诊时接受了HRCT和肺功能评估。对吸气和呼气HRCT进行评估，以确定空气潴留、磨玻璃样混浊、结节、间隔增厚、支气管扩张和实质扭曲的存在情况及范围。将HRCT特征与肺功能测试结果相关联。
21例患者中有20例（95%）在呼气HRCT上存在空气潴留。空气潴留的范围与预测残气量（RV）/肺总量（TLC）百分比（r = 0.499；P < 0.05）以及肺活量25%至75%之间的预测最大呼气中期流速百分比（r = -0.54；P < 0.05）相关。21例患者中有4例（19%）存在磨玻璃样混浊，18例（86%）存在结节，18例（86%）存在间隔增厚，14例（67%）存在牵拉性支气管扩张，12例（57%）存在实质扭曲；这些CT特征与肺功能结果之间无显著相关性。
空气潴留是结节病的常见特征，与肺功能测试中提示小气道疾病的证据相关。
Zotero 插件