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[人类小脑皮质颗粒层在出生后个体发育中的模块化组织]

[The modular organization of the granular layer of the human cerebellar cortex in postnatal ontogeny].

作者信息

Tsekhmistrenko T A

机构信息

Laboratory of Functional Morphology, Russian Academy of Education, Moscow.

出版信息

Morfologiia. 1999;116(6):15-9.

Abstract

Age changes of microstructure of granular layer of the cortex of human cerebellum superior lobe (the area of clivus, posterior lateral regions of right and left tetrangular lobules) were studied in annual intervals from birth up to 20 yrs using computer analysis of optic images. Enlargement of the area of profile fields of cell groups in apical and basal regions of cerebellar folia from birth up to 14-15 yrs and differences between hemispheres in clasterization of granular layer were demonstrated. The data on age changes of cellular aggregations obtained allowed to formulate a hypothesis on autonomic local sensory networks of human cerebellar cortex associated with granular layer of cerebellar cortex that are considered as structural elements of module organization of the latter.

摘要

利用光学图像的计算机分析,对人类小脑上叶皮质颗粒层(斜坡区域、左右四角小叶后外侧区域)从出生到20岁每隔一年的微观结构年龄变化进行了研究。结果表明,从出生到14 - 15岁,小脑叶片顶端和基部区域细胞群轮廓场面积增大,且颗粒层聚类在半球之间存在差异。所获得的关于细胞聚集年龄变化的数据,使得人们能够提出一个关于人类小脑皮质自主局部感觉网络的假说,该网络与小脑皮质颗粒层相关,而颗粒层被认为是小脑皮质模块组织的结构要素。

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