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模块化过渡种植体的即刻加载:犬类的组织学和组织形态计量学研究

Immediate loading of modular transitional implants: a histologic and histomorphometric study in dogs.

作者信息

Zubery Y, Bichacho N, Moses O, Tal H

机构信息

Department of Prosthetic Dentistry, Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Israel.

出版信息

Int J Periodontics Restorative Dent. 1999 Aug;19(4):343-53.

PMID:10709501
Abstract

Modular Transitional Implants (MTI) are made from pure titanium and are used to support fixed provisional restorations during the osseointegration of definitive implants. This study histologically examined the jaw response to loaded MTIs in the dog mandible. Three implants were inserted transmucosally into each side of the mandible in 3 dogs. Stability was examined using a Periotest. Anterior and posterior implants were splinted using a cemented acrylic resin fixed partial denture to allow immediate loading. The middle implant remained unloaded and was used as a control. Dogs were sacrificed 11 to 12 weeks after implantation, and tissue blocks containing the implants were removed. Histologic examination showed that 10 of the 18 implants had good bone-to-implant contact, with the percentage of bone contacting the threaded portion of the implant varying from 30% to 65%. There was no statistical difference (p > 0.1) in percentage of bone-to-metal contact between loaded and unloaded implants. Six implants were entirely surrounded by connective tissue with or without inflammation; two implants were lost during the study. The success rate did not differ between loaded and unloaded implants. In the successful implants trabecular bone made good contact with the implant, forming supporting struts. There was bone remodeling in some bone-to-metal contact areas. It is believed that success was mainly influenced by the initial bone density at the implant site and by the uncontrolled load that the animals applied to the implants during the early healing stage.

摘要

模块化过渡种植体(MTI)由纯钛制成,用于在确定性种植体骨整合期间支持固定临时修复体。本研究通过组织学检查了犬下颌骨中加载MTI后的颌骨反应。在3只犬的下颌骨两侧经黏膜各植入3枚种植体。使用牙周探针检查稳定性。前后种植体用粘结丙烯酸树脂固定局部义齿进行夹板固定,以便立即加载。中间的种植体不加载,用作对照。植入后11至12周处死犬,取出包含种植体的组织块。组织学检查显示,18枚种植体中有10枚骨与种植体接触良好,与种植体螺纹部分接触的骨百分比在30%至65%之间。加载和未加载的种植体之间骨与金属接触的百分比无统计学差异(p>0.1)。6枚种植体完全被结缔组织包围,伴有或不伴有炎症;2枚种植体在研究期间丢失。加载和未加载的种植体成功率无差异。在成功的种植体中,松质骨与种植体良好接触,形成支撑支柱。在一些骨与金属接触区域有骨重塑。据信,成功主要受种植体部位的初始骨密度以及动物在早期愈合阶段施加于种植体的不受控制的负荷影响。

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