Ulloa R E, Birmaher B, Axelson D, Williamson D E, Brent D A, Ryan N D, Bridge J, Baugher M
Division of Child Psychiatry, University of Pittsburgh Medical Center, USA.
J Am Acad Child Adolesc Psychiatry. 2000 Mar;39(3):337-45. doi: 10.1097/00004583-200003000-00016.
To examine the demographics and phenomenology of psychosis in a sample of children and adolescents referred to a mood and anxiety disorders clinic.
Patients (N = 2,031) were assessed with the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present Episode version and classified as definite, probable, or nonpsychotic. Clinical and demographic characteristics of the groups were compared,and symptoms of psychosis were analyzed using factor analysis.
Definite psychotic symptoms were seen in approximately 90 (4.5%) patients: 80% of these reported hallucinations (mainly auditory), 22% delusions, and 3.3% thought disorder. Of the patients with definite psychotic symptoms, 24% had bipolar disorder, 41% had major depression, 21% had subsyndromal depression, and 14% had schizophrenia spectrum disorders (schizophrenia and schizoaffective disorders). Factor analysis of the definite psychotic symptoms yielded 4 factors: hallucinations, thought disorder, delusions, and manic thought disorder. Psychotic patients had a higher frequency of comorbid disorders and suicidal ideation than nonpsychotic patients.
Outpatient youngsters with mood disorders frequently present with psychotic symptoms, in particular auditory hallucinations. These patients commonly have comorbid psychiatric disorders and suicidal ideation.
在转诊至情绪与焦虑障碍门诊的儿童及青少年样本中,研究精神病的人口统计学特征及现象学。
使用《学龄儿童情感障碍和精神分裂症评定量表(当前发作版)》对2031名患者进行评估,并将其分类为确诊、疑似或非精神病性。比较各组的临床和人口统计学特征,并使用因子分析对精神病症状进行分析。
约90名(4.5%)患者出现确诊的精神病症状:其中80%报告有幻觉(主要是幻听),22%有妄想,3.3%有思维障碍。在有确诊精神病症状的患者中,24%患有双相情感障碍,41%患有重度抑郁症,21%患有亚综合征性抑郁症,14%患有精神分裂症谱系障碍(精神分裂症和分裂情感性障碍)。对确诊精神病症状进行因子分析得出4个因子:幻觉、思维障碍、妄想和躁狂思维障碍。与非精神病性患者相比,精神病性患者共病障碍和自杀观念的发生率更高。
患有情绪障碍的门诊青少年经常出现精神病症状,尤其是幻听。这些患者通常伴有共病精神障碍和自杀观念。