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思维紊乱。精神分裂症、躁狂症或精神病的一种表现?

Thought disorder. A function of schizophrenia, mania, or psychosis?

作者信息

Marengo J, Harrow M

出版信息

J Nerv Ment Dis. 1985 Jan;173(1):35-41.

PMID:3965610
Abstract

Does thought disorder emerge solely as a function of psychosis, or is it a function of diagnosis? The present research investigated whether thought disorder is more frequent in specific diagnostic groups, such as schizophrenia and mania, than in other types of psychotic disorders. The frequency and severity of positive thought disorder was assessed in 324 Research Diagnostic Criteria and DSM-III schizophrenics, manics, other psychotic patients, and nonpsychotic patients, and a normal comparison group. Fifty-seven percent of the sample were first hospital admissions. Patients were tested at the acute phase of their disorder, within the first 2 weeks of hospitalization, with three cognitive tests. Scores from these three tests were scaled to obtain a composite index of the severity of positive thought disorder. Diagnostic factors were more salient to the severity of disordered thinking than was psychosis. Thought disorder was significantly more frequent in schizophrenia and mania than in other psychotic disorders (p less than .05). The frequency of patients with severe thought disorder was reduced as one moved down the hierarchy of manic, schizophrenic, schizoaffective, and depressed psychotic disturbances (p less than .001). Rather surprisingly, the current research suggests that nonpsychotic manic patients may be as thought disordered as psychotic manic patients at acute phases of disturbance. This would indicate that the presence of positive thought disorder in mania is not primarily a function of most of these patients' being psychotic at the acute phase of disturbance. Thought disorder was not simply a function of psychosis.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

思维紊乱仅仅是精神病的一种表现,还是诊断的一种结果?本研究调查了在特定诊断组(如精神分裂症和躁狂症)中,思维紊乱是否比其他类型的精神障碍更常见。对324名符合研究诊断标准和《精神疾病诊断与统计手册》第三版(DSM-III)的精神分裂症患者、躁狂症患者、其他精神病患者、非精神病患者以及一个正常对照组,评估了阳性思维紊乱的频率和严重程度。样本中有57%是首次入院患者。在患者疾病急性期,即住院的前两周内,用三项认知测试对他们进行检测。对这三项测试的分数进行换算,以获得阳性思维紊乱严重程度的综合指数。与精神病相比,诊断因素对思维紊乱严重程度的影响更为显著。精神分裂症和躁狂症患者的思维紊乱明显比其他精神病患者更常见(p<0.05)。随着从躁狂症、精神分裂症、分裂情感性障碍和抑郁性精神障碍的等级依次降低,严重思维紊乱患者的频率也随之降低(p<0.001)。相当令人惊讶的是,当前研究表明,在紊乱急性期,非精神病性躁狂症患者的思维紊乱程度可能与精神病性躁狂症患者一样。这表明,躁狂症中阳性思维紊乱的存在,并非主要是因为这些患者在紊乱急性期大多患有精神病。思维紊乱并非仅仅是精神病的一种表现。(摘要截选至250词)

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