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海洋天然产物化学研究亮点(1972 - 1999年)。

Highlights of marine natural products chemistry (1972-1999).

作者信息

Faulkner D J

机构信息

Scripps Institution of Oceanography, University of California at San Diego, La Jolla 92093-0212, USA.

出版信息

Nat Prod Rep. 2000 Feb;17(1):1-6. doi: 10.1039/a909113k.

Abstract

Marine Natural Products Chemistry is essentially a child of the 1970's that developed rapidly during the 1980's and matured in the last decade. With a few notable exceptions, it is difficult to select individual papers that significantly impacted the field. However, marine natural products chemistry has often influenced other fields and that aspect is the focus of this review. It is clear that the early directions taken by marine natural products chemists drew as much from the examples provided by insect chemical ecology as from the longer history of phytochemistry. By 1975 there were already three parallel tracks in marine natural products chemistry: marine toxins, marine biomedicinals and marine chemical ecology. It is the integration of the three fields of study that has given marine natural products chemistry its unique character and vigour.

摘要

海洋天然产物化学本质上是20世纪70年代的产物,在80年代迅速发展,并在过去十年中走向成熟。除了少数显著的例外,很难挑选出对该领域有重大影响的个别论文。然而,海洋天然产物化学常常影响其他领域,而这正是本综述的重点。很明显,海洋天然产物化学家早期的研究方向,既借鉴了昆虫化学生态学提供的例子,也借鉴了历史更为悠久的植物化学。到1975年,海洋天然产物化学已经有三条并行的研究路径:海洋毒素、海洋生物药物和海洋化学生态学。正是这三个研究领域的整合,赋予了海洋天然产物化学独特的性质和活力。

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