Egenvall A, Bonnett B N, Gunnarsson A, Hedhammar A, Shoukri M, Bornstein S, Artursson K
Department of Small Animal Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala.
Scand J Infect Dis. 2000;32(1):19-25. doi: 10.1080/00365540050164164.
In Sweden, 2 tick-borne zoonotic diseases, granulocytic ehrlichiosis and borreliosis, are frequently diagnosed in dogs, using serological assays. The aims of this study were to determine the sero-prevalences of antibodies to Ehrlichia spp. and Borrelia burgdorferi sensu lato during 1991-94 in dogs, not clinically suspected to be infected with either of the 2 agents. Samples (n = 611) were selected from a serum bank using a systematic sampling strategy, stratified across the 4-y period. The stored sera had originally been submitted in order to verify or rule out infection with Sarcoptes scabiei. The overall sero-prevalence for Ehrlichia spp. was 17.7% and for Borrelia burgdorferi sensu lato 3.9% (n = 588). Only a few dogs in the northern part of Sweden were sero-positive for Ehrlichia spp. and none were positive for Borrelia burgdorferi sensu lato. An increased sero-prevalence of Ehrlichia spp. was seen during the years studied. The sero-prevalence of Ehrlichia spp. varied with season. Sero-positivity to both agents increased with age. Both diseases are considered zoonotic, and the increase in sero-prevalence of Ehrlichia spp. over the years may reflect the degree of infection in ticks and may have implications for human health.
在瑞典，通过血清学检测，犬类中常被诊断出两种蜱传人畜共患病，即粒细胞埃立克体病和莱姆病。本研究的目的是确定1991年至1994年期间未临床怀疑感染这两种病原体的犬类中抗埃立克体属抗体和广义伯氏疏螺旋体抗体的血清阳性率。采用系统抽样策略从血清库中选取样本（n = 611），并按4年时间分层。储存的血清最初是为了验证或排除疥螨感染而提交的。埃立克体属的总体血清阳性率为17.7%，广义伯氏疏螺旋体为3.9%（n = 588）。瑞典北部只有少数犬类埃立克体属血清呈阳性，广义伯氏疏螺旋体均无阳性。在所研究的年份中，埃立克体属的血清阳性率有所增加。埃立克体属的血清阳性率随季节变化。两种病原体的血清阳性率均随年龄增长而增加。这两种疾病均被视为人畜共患病，多年来埃立克体属血清阳性率的增加可能反映了蜱虫的感染程度，对人类健康可能有影响。
