母牛血清抗体与犊牛抵抗牛轮状病毒腹泻的保护作用之间的相关性。
Correlation between maternal serum antibodies and protection against bovine rotavirus diarrhea in calves.
作者信息
Kohara J, Tsunemitsu H
机构信息
Shintoku Animal Husbandry Experiment Station, Hokkaido, Japan.
出版信息
J Vet Med Sci. 2000 Feb;62(2):219-21. doi: 10.1292/jvms.62.219.
The correlation between maternal serum antibodies in beef calves at 2 days old and protection against diarrhea induced by natural bovine rotavirus (BRV) infection was examined. Virus neutralizing (VN) antibody titers against BRV in sera from calves that developed diarrhea by BRV infection within 14 days of age (BRV-diarrheal calves) were significantly lower than those from calves that had no diarrhea. In the BRV-diarrheal calves, a positive correlation was found between the VN antibody titers and age of the onset of diarrhea. There were negative correlations between the VN antibody titers and duration of the diarrhea, VN antibody titers and cumulative diarrhea scores, and the VN antibody titers and duration of virus shedding. These results suggest that the VN antibody titers against BRV in newborn calf serum could be an indicator of protection against BRV-induced diarrhea.
研究了2日龄犊牛血清抗体与天然牛轮状病毒（BRV）感染所致腹泻保护作用之间的相关性。14日龄内发生BRV感染性腹泻的犊牛（BRV腹泻犊牛）血清中针对BRV的病毒中和（VN）抗体滴度显著低于未发生腹泻的犊牛。在BRV腹泻犊牛中，VN抗体滴度与腹泻发病年龄呈正相关。VN抗体滴度与腹泻持续时间、VN抗体滴度与累积腹泻评分以及VN抗体滴度与病毒 shedding 持续时间之间均呈负相关。这些结果表明，新生犊牛血清中针对BRV的VN抗体滴度可能是预防BRV诱导腹泻的一个指标。 （注：原文中“shedding”可能是“排毒”之类的专业术语，因不确定准确含义，保留英文）
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