Smith W, Mitchell P, Leeder S R
National Centre for Epidemiology and Population Health, Australian National University, Australian Capital Territory.
Arch Ophthalmol. 2000 Mar;118(3):401-4. doi: 10.1001/archopht.118.3.401.
To assess whether dietary intake of fat or fish is associated with age-related maculopathy (ARM) prevalence.
Cross-sectional, urban population-based study.
People (N = 3654) aged 49 years or older.
Subjects with ARM were identified from masked grading of retinal photographs. A 145-itemself-administered, semiquantitative food frequency questionnaire was completed adequately by 88.8% of participants and was used to assess intakes of dietary fat and fish.
A higher frequency of fish consumption was associated with decreased odds of late ARM (odds ratio for frequency of consumption more than once per week compared with less than once per month, 0.5). Subjects with higher energy-adjusted intakes of cholesterol were significantly more likely to have late ARM, with an increased risk for late ARM for the highest compared with the lowest quintile of intake (odds ratio, 2.7).
The amount and type of dietary fat intake may be associated with ARM.
评估膳食中脂肪或鱼类的摄入量是否与年龄相关性黄斑病变（ARM）的患病率相关。
基于城市人群的横断面研究。
49岁及以上的人群（N = 3654）。
通过对视网膜照片进行盲法分级来确定患有ARM的受试者。88.8%的参与者充分完成了一份145项的自填式半定量食物频率问卷，该问卷用于评估膳食脂肪和鱼类的摄入量。
较高频率的鱼类消费与晚期ARM的患病几率降低相关（每周食用频率超过一次与每月食用频率低于一次相比，优势比为0.5）。胆固醇能量调整摄入量较高的受试者患晚期ARM的可能性显著更高，摄入量最高五分位数与最低五分位数相比，晚期ARM的风险增加（优势比，2.7）。
膳食脂肪摄入的量和类型可能与ARM相关。
