用于评估反应性关节炎的疾病活动指数（DAREA）的开发。
Development of a disease activity index for the assessment of reactive arthritis (DAREA).
作者信息
Eberl G, Studnicka-Benke A, Hitzelhammer H, Gschnait F, Smolen J S
机构信息
Division of Rheumatology, Department of Internal Medicine III, University of Vienna, Austria.
出版信息
Rheumatology (Oxford). 2000 Feb;39(2):148-55. doi: 10.1093/rheumatology/39.2.148.
OBJECTIVES
The objectives of this study were to investigate and validate individual variables and to develop a composite score for disease activity measurement in patients with reactive arthritis (REA).
METHODS
In the first cross-sectional part, the clinical and laboratory evaluation of 45 patients was used to elaborate the most important individual disease activity measures. In the second prospective part, these variables as well as a composite score for disease activity measurement of REA were prospectively validated in 23 patients at two points in time.
RESULTS
The following variables emerged as the most useful for the composite measure: number of swollen and tender joints, patient's pain and global assessment, and C-reactive protein. The score was calculated by simple addition of the individual figures.
CONCLUSION
DAREA constitutes a reliable score which can easily be assessed on a day-to-day office work basis.
目的
本研究的目的是调查和验证个体变量，并开发一种用于反应性关节炎（REA）患者疾病活动度测量的综合评分。
方法
在第一个横断面部分，对45例患者进行临床和实验室评估，以确定最重要的个体疾病活动度测量指标。在第二个前瞻性部分，这些变量以及REA疾病活动度测量的综合评分在23例患者的两个时间点进行了前瞻性验证。
结果
以下变量被证明对综合测量最有用：肿胀和压痛关节的数量、患者的疼痛和整体评估以及C反应蛋白。该评分通过简单相加各个数值来计算。
结论
DAREA是一个可靠的评分，可在日常门诊工作中轻松评估。
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