Ivanova R, Veselinova T, Marinov E, Gorchev G, Tsetkov Ch, Lalov S
Akush Ginekol (Sofiia). 1999;38(4):35-7.
A retrospective morphological research is made on the material of 78 cases from vulva for a three years period of time. They are identified 35 cases with invasive carcinoma, 2 c. with noninvasive carcinoma, 19 c. with vulvar dystrophia and squamous intraepithelial neoplasia (VIN). The invasive carcinomas are divided: keratinizing squamous cell carcinoma--31 c.; nonkeratinizing squamous cell carcinoma--3 c; adenoid squamous cell carcinoma--1. In all operated patients are examined the changes in the tissues surrounding the tumor and in the underlying tissue. They are divided in: lichen sclerosus, squamous cell hyperplasia, mixed dystrophia and squamous intraepithelial neoplasia. The morphological variants of squamous carcinoma, the epithelial changes and the patient's age are paralleled.
对78例三年来外阴病变的材料进行回顾性形态学研究。其中确诊为浸润性癌35例，非浸润性癌2例，外阴营养不良及鳞状上皮内瘤变（VIN）19例。浸润性癌分为：角化性鳞状细胞癌31例；非角化性鳞状细胞癌3例；腺样鳞状细胞癌1例。对所有手术患者检查肿瘤周围组织及深层组织的变化。这些变化分为：硬化性苔藓、鳞状细胞增生、混合性营养不良及鳞状上皮内瘤变。鳞状细胞癌的形态学变异、上皮变化与患者年龄相关。
