Murta E F, Resende A V, Souza M A, Adad S J, Salum R
Discipline of Gynecology and Obstetrics, Faculty of Medicine of Triângulo Mineiro, Uberaba, MG, Brazil.
Arch Gynecol Obstet. 1999 Nov;263(1-2):42-4. doi: 10.1007/s004040050260.
We conducted a retrospective study on 201 conizations for CIN III done over the last 14 years. Of these, 53 (26.4%) had involvement of the margins, 114 (56.7%) had margins free of neoplasia, and 34 (16.9%) were not evaluated. Of the 53 cases with margin involvement, 28 (52.8%) had complementary surgery and 25 (47.2%) cytological follow-up. Residual CIN was identified in the surgical specimen in 15 cases (53.6%) and microinvasion was present in 2 cases (7.1%). Of the 114 patients with margins free of neoplasia in the cone, 12 had a hysterectomy during follow-up for CIN III diagnosed by cytology and biopsy. Seven of these 12 patients (58.3%) had CIN in the surgical specimen and none had microinvasive cancer.
我们对过去14年中进行的201例CIN III宫颈锥切术进行了回顾性研究。其中，53例（26.4%）切缘受累，114例（56.7%）切缘无肿瘤，34例（16.9%）未评估切缘情况。在53例切缘受累的病例中，28例（52.8%）接受了补充手术，25例（47.2%）进行了细胞学随访。手术标本中发现15例（53.6%）有残留CIN，2例（7.1%）有微浸润。在114例锥切切缘无肿瘤的患者中，12例在随访期间因细胞学和活检诊断为CIN III而行子宫切除术。这12例患者中有7例（58.3%）手术标本中有CIN，无一例有微浸润癌。
