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Geburtshilfe Frauenheilkd. 2016 Dec;76(12):1339-1344. doi: 10.1055/s-0042-113773. Epub 2016 Sep 5.
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A comparison between type 3 excision of the transformation zone by straight wire excision of the transformation zone (SWETZ) and large loop excision of the transformation zone (LLETZ): a randomized study.转化区直丝切除术(SWETZ)与转化区大环状切除术(LLETZ)治疗转化区3型切除术的比较:一项随机研究。
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本文引用的文献

1
Does the number of tissue fragments removed from the cervix with excisional treatment for CIN pathology affect the completeness of excision and cytology recurrence at follow-up? An observational cohort study.对于CIN病理采用切除治疗时,从宫颈切除的组织碎片数量是否会影响切除的完整性以及随访时的细胞学复发情况?一项观察性队列研究。
J Obstet Gynaecol. 2016;36(2):251-6. doi: 10.3109/01443615.2015.1060202. Epub 2015 Oct 12.
2
Quality evaluation of cone biopsy specimens obtained by large loop excision of the transformation zone.转化区大环形切除术获取的宫颈锥切标本的质量评估
J Clin Med Res. 2015 Apr;7(4):220-4. doi: 10.14740/jocmr1951w. Epub 2015 Feb 9.
3
Proportion of cervical excision for cervical intraepithelial neoplasia as a predictor of pregnancy outcomes.宫颈上皮内瘤变宫颈切除术比例作为妊娠结局预测指标
Int J Gynaecol Obstet. 2015 Feb;128(2):141-7. doi: 10.1016/j.ijgo.2014.07.038. Epub 2014 Oct 2.
4
LLETZ Specimen Fragmentation: Impact on Diagnosis, Outcome, and Implications for Training.大环状电切术标本碎片化:对诊断、结果及培训的影响
J Obstet Gynaecol India. 2013 Oct;63(5):332-6. doi: 10.1007/s13224-012-0332-8. Epub 2013 Mar 26.
5
Surgery for cervical intraepithelial neoplasia.宫颈上皮内瘤变的手术治疗
Cochrane Database Syst Rev. 2013 Dec 4;2013(12):CD001318. doi: 10.1002/14651858.CD001318.pub3.
6
Appropriate cone dimensions to achieve negative excision margins after large loop excision of transformation zone in the uterine cervix for cervical intraepithelial neoplasia.合适的锥形尺寸以实现宫颈上皮内瘤变的子宫颈大圈切除术(loop excision of transformation zone,LLETZ)后的负切缘。
Gynecol Obstet Invest. 2013;75(3):163-8. doi: 10.1159/000345864. Epub 2012 Dec 28.
7
Assessment of cervical intraepithelial neoplasia (CIN) with colposcopic biopsy and efficacy of loop electrosurgical excision procedure (LEEP).宫颈上皮内瘤变(CIN)的评估与阴道镜下活检和环形电切术(LEEP)的疗效。
Arch Gynecol Obstet. 2012 Dec;286(6):1549-54. doi: 10.1007/s00404-012-2493-1. Epub 2012 Aug 3.
8
Conization of the uterine cervix: does the level of gynecologist's training predict margin status?子宫颈锥切术:妇科医生的培训水平是否可预测切缘状态?
Int J Gynecol Pathol. 2012 Jul;31(4):382-6. doi: 10.1097/PGP.0b013e318242118c.
9
Number of fragments, margin status and thermal artifacts of conized specimens from LLETZ surgery to treat cervical intraepithelial neoplasia.用于治疗宫颈上皮内瘤变的LEETZ手术中锥切标本的碎片数量、切缘状态及热效应伪影
Sao Paulo Med J. 2012;130(2):92-6. doi: 10.1590/s1516-31802012000200004.
10
Thermal artifact after three techniques of loop excision of the transformation zone: a comparative study.三种转化区环形电切术的热损伤:一项对比研究。
Gynecol Obstet Invest. 2012;73(3):230-5. doi: 10.1159/000333438. Epub 2012 Mar 21.

外科医生的阴道镜检查经验在育龄期女性转化区大环形切除术获取足够样本中的作用。

The Role of Surgeons' Colposcopic Experience in Obtaining Adequate Samples by Large Loop Excision of the Transformation Zone in Women of Reproductive Age.

作者信息

Sparić R, Tinelli A, Guido M, Stefanović R, Babović I, Kesić V

机构信息

Clinic for Gynecology and Obstetrics, Clinical Centre of Serbia, Belgrade, Serbia; School of Medicine, University of Belgrade, Belgrade, Serbia.

International Translational Medicine and Biomodeling Research Group Department of Applied Mathematics, Moscow Institute of Physics and Technology (State University), Moscow, Russia; Division of Experimental Endoscopic Surgery, Imaging, Technology and Minimally Invasive Therapy of Centre for Interdisciplinary Research Applied to Medicine Department of Obstetrics and Gynecology Vito Fazzi Hospital, Lecce, Italy.

出版信息

Geburtshilfe Frauenheilkd. 2016 Dec;76(12):1339-1344. doi: 10.1055/s-0042-113773. Epub 2016 Sep 5.

DOI:10.1055/s-0042-113773
PMID:28017975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5177550/
Abstract

There is insufficient reporting on the level of colposcopic training for the safe use of large loop excision of the transformation zone. The aim of this study was to perform a quality assessment of large loop excision of the transformation zone in women of reproductive age by evaluating the surgeons' colposcopic experience. A retrospective cohort study was performed on diagnostic or therapeutic large loop excision of the transformation zone. The following variables were analyzed: age, parity, indications for surgery, level of surgeon's colposcopic experience, definitive histological diagnosis, margin involvement, and the presence and type of artifacts interfering with the pathological interpretation. Patients were divided into three groups: group A - 75 patients treated by junior colposcopists; group B - 74 patients treated by experienced colposcopists, and group C - 117 patients treated by expert colposcopists. Regarding the presence and diagnostic significance of the artifacts the groups were significantly different. Inadequate samples were the least frequent in group C. Artifacts precluding histological diagnosis were the most common in group A. The margins were predominantly inconclusive in group A. A high rate of artifacts is a disadvantage of the large loop excision of the transformation zone performed by surgeons less skilled for colposcopy. Although large loop excision of the transformation zone is considered to be a minor surgery, skills in colposcopy are an essential prerequisite for optimal results.

摘要

关于转化区大环形切除术安全使用的阴道镜培训水平,报告不足。本研究的目的是通过评估外科医生的阴道镜经验,对育龄妇女的转化区大环形切除术进行质量评估。对转化区的诊断性或治疗性大环形切除术进行了一项回顾性队列研究。分析了以下变量:年龄、产次、手术指征、外科医生的阴道镜经验水平、最终组织学诊断、切缘受累情况以及干扰病理解读的伪像的存在和类型。患者分为三组:A组——75例由初级阴道镜检查医生治疗的患者;B组——74例由经验丰富的阴道镜检查医生治疗的患者;C组——117例由专家级阴道镜检查医生治疗的患者。关于伪像的存在及其诊断意义,各组之间存在显著差异。C组中样本不足的情况最少见。妨碍组织学诊断的伪像在A组中最为常见。A组中切缘大多不确定。伪像发生率高是阴道镜操作技能较低的外科医生进行转化区大环形切除术的一个缺点。尽管转化区大环形切除术被认为是一个小手术,但阴道镜检查技能是取得最佳效果的必要前提。