Rozenberg F
Laboratoire de virologie Hôpital Saint-Vincent-de-Paul, Paris.
Rev Prat. 1999 Dec 15;49(20):2197-202.
The human herpesviruses share common structural and biological properties. After primary infection, they remain in a latent state during the life-time. Whereas infections are most often benign in immunocompetent individuals, severe infectious or tumoral complications may occur particularly in patients with cellular immunodeficiencies. Anti-viral drugs target viral replication, but have no effect on latency, which remains poorly understood.
人类疱疹病毒具有共同的结构和生物学特性。初次感染后，它们在宿主体内终生处于潜伏状态。在免疫功能正常的个体中，感染通常是良性的，但在细胞免疫缺陷患者中，可能会出现严重的感染或肿瘤并发症。抗病毒药物针对病毒复制起作用，但对潜伏状态无效，而潜伏状态仍知之甚少。
