从一名肺曲菌球患者栓塞术后血样中分离出的烟曲霉。

Aspergillus fumigatus isolated from blood samples of a patient with pulmonary aspergilloma after embolization.

作者信息

Seki M, Maesaki S, Hashiguchi K, Tomiyama Y, Tomono K, Tashiro T, Kohno S

机构信息

Second Department of Internal Medicine, Nagasaki University School of Medicine.

出版信息

Intern Med. 2000 Feb;39(2):188-90. doi: 10.2169/internalmedicine.39.188.

DOI:10.2169/internalmedicine.39.188

PMID:10732844

Abstract

Aspergillus DNA was detected by PCR in the serum sample of a 78-year-old man and galactomannan antigen of Aspergillus by sandwich ELISA was found. However, the infiltrative hyphae were not detected by the histopathologic examination of the lung. He developed hemoptysis, which required embolization of bronchial arteries. Aspergillus fumigatus was isolated from blood samples after embolization by the lysis centrifugation method. To our knowledge, this is probably the first case in which Aspergillus spp. has been isolated from the systemic circulatory blood in a patient with pulmonary aspergilloma after embolization.

摘要

在一名78岁男性的血清样本中通过聚合酶链反应（PCR）检测到曲霉菌DNA，并通过夹心酶联免疫吸附测定（ELISA）发现了曲霉菌的半乳甘露聚糖抗原。然而，肺部组织病理学检查未检测到浸润性菌丝。他出现了咯血，需要进行支气管动脉栓塞术。栓塞术后通过裂解离心法从血样中分离出烟曲霉。据我们所知，这可能是首例在肺曲菌球患者栓塞术后从体循环血液中分离出曲霉菌属的病例。