Müller B T, Grabitz K, Fürst G, Sandmann W
Klinik für Gefässchirurgie und Nierentransplantation, Heinrich-Heine-Universität Düsseldorf.
Chirurg. 2000 Feb;71(2):209-14. doi: 10.1007/s001040051039.
About 30% of the patients with acute aortic dissection suffer from organ or limb ischemia. We analyzed the influence of ischemic localization and method of operative treatment (aortic fenestration or extraanatomic bypass revascularization) on morbidity and mortality.
From 1 May 1987 to 31 December 1998 21 patients with 24 vascular complications such as renal or intestinal ischemia, lower extremity ischemia and paraplegia following acute aortic dissection were treated at our institution. Recruitment was retrospective in 16 and prospective in 5 patients. In 5 patients (24%) the complication was associated with Stanford A, in 16 (76%) with Stanford B dissection. Ten patients (48%) complained of malperfusion of only one region, whereas 11 patients (52%) suffered from ischemia of two or three different regions. Aortic fenestration and resection of the dissected membrane was performed in nine cases (37%). Fifteen patients (63%) were treated with extraanatomic bypass techniques.
One third of the patients died, four of them due to aortic penetration or perforation and two due to visceral ischemia. During follow-up of 32 (1-110) months two patients developed aortic complications. One died of aortic perforation, while the other developed a thoracoabdominal aneurysm and had to be treated by a tube graft replacement.
Outcome depended more on the spontaneous course of aortic dissection and on prompt diagnosis and therapy of the complications than on the different operative techniques.
约30%的急性主动脉夹层患者会出现器官或肢体缺血。我们分析了缺血部位和手术治疗方法(主动脉开窗或解剖外旁路血管重建)对发病率和死亡率的影响。
1987年5月1日至1998年12月31日,我院共治疗了21例急性主动脉夹层后出现24种血管并发症的患者,如肾或肠缺血、下肢缺血和截瘫。16例患者为回顾性招募,5例为前瞻性招募。5例患者(24%)的并发症与斯坦福A型相关,16例(76%)与斯坦福B型夹层相关。10例患者(48%)仅抱怨一个区域灌注不良,而11例患者(52%)患有两个或三个不同区域的缺血。9例患者(37%)进行了主动脉开窗和剥离膜切除术。15例患者(63%)采用解剖外旁路技术治疗。
三分之一的患者死亡,其中4例死于主动脉穿透或穿孔,2例死于内脏缺血。在32(1 - 110)个月的随访期间,2例患者出现主动脉并发症。1例死于主动脉穿孔,另1例发展为胸腹主动脉瘤,不得不接受人工血管置换治疗。
结果更多地取决于主动脉夹层的自然病程以及并发症的及时诊断和治疗,而非不同的手术技术。