Banerjee Prerana, Theus Christoph, Bremerich Jens, Wolff Thomas, Reuthebuch Oliver, Eckstein Friedrich, Matt Peter
Division of Cardiac Surgery, University Hospital, Basel, Switzerland.
Department of Radiology, University Hospital, Basel, Switzerland.
Thorac Cardiovasc Surg. 2016 Mar;64(2):108-15. doi: 10.1055/s-0035-1548732. Epub 2015 Apr 13.
We hypothesized that preoperative computed tomography (CT) is a predictor of abdominal intervention for visceral malperfusion and stroke after emergent surgery for acute type A aortic dissection (AAAD).
A total of 90 patients, mean (± SD [standard deviation]) age 62 (± 12) years, 76% males, undergoing emergent surgery for AAAD at our institution from May 2008 to August 2013 were included. All clinical data were collected prospectively and correlated to CT images.
At initial presentation 9 (10%) patients showed preoperative focal neurologic deficit or coma, 10 patients (11%) complained of abdominal pain, and the logistic EuroSCORE was 44 (± 22). Hemiarch replacement was performed in 96%, total arch in 4%. The duration of hypothermic circulatory arrest (HCA) at 28°C bladder temperature was 26 (± 19) minutes. Cross-clamp time was 88 (± 39) minutes, and cardiopulmonary bypass (CPB) time 148 (± 49) minutes. Overall 30-day mortality was 13%. Moreover, 12 (13%) patients required postoperative abdominal interventions for suspected visceral malperfusion; stroke occurred in 25 (28%) patients. Logistic regression revealed that "dissection of the celiac trunk and/or the superior mesenteric artery" in preoperative CT images is a predictor of postoperative abdominal interventions for visceral malperfusion (p = 0.03), but preoperative abdominal pain is not similarly predictive. Postoperative stroke is best predicted by preoperative neurologic symptoms (p = 0.01), but not by supra-aortic vessel dissection in preoperative CT images.
In patients undergoing surgery for AAAD, analysis of preoperative CT images allows identifying those with a high risk of postoperative abdominal intervention for visceral malperfusion. Postoperative stroke is best predicted by preoperative neurologic symptoms.
我们推测,术前计算机断层扫描(CT)可作为急性A型主动脉夹层(AAAD)急诊手术后内脏灌注不良和中风进行腹部干预的预测指标。
纳入2008年5月至2013年8月在我院接受AAAD急诊手术的90例患者,平均(±标准差[SD])年龄62(±12)岁,男性占76%。所有临床数据均前瞻性收集,并与CT图像相关联。
初次就诊时,9例(10%)患者出现术前局灶性神经功能缺损或昏迷,10例(11%)患者主诉腹痛,逻辑欧洲心脏手术风险评估系统(EuroSCORE)评分为44(±22)。96%的患者进行了半弓置换,4%的患者进行了全弓置换。膀胱温度28°C时的低温循环停搏(HCA)持续时间为26(±19)分钟。夹闭时间为88(±39)分钟,体外循环(CPB)时间为148(±49)分钟。总体30天死亡率为13%。此外,12例(13%)患者因疑似内脏灌注不良需要术后腹部干预;25例(28%)患者发生中风。逻辑回归显示,术前CT图像中“腹腔干和/或肠系膜上动脉夹层”是术后因内脏灌注不良进行腹部干预的预测指标(p = 0.03),但术前腹痛并非类似的预测指标。术后中风的最佳预测指标是术前神经症状(p = 0.01),而非术前CT图像中的主动脉弓上血管夹层。
在接受AAAD手术的患者中,术前CT图像分析有助于识别术后因内脏灌注不良进行腹部干预风险较高的患者。术后中风的最佳预测指标是术前神经症状。