克拉维酸增强型阿莫西林对犬精液质量的影响。
Effect of clavulanic acid-potentiated amoxycillin on semen quality in dogs.
作者信息
England G C
机构信息
Department of Farm Animal and Equine Medicine and Surgery, Royal Veterinary College, University of London, Hatfield, Herts, England.
出版信息
Theriogenology. 1999 Nov;52(7):1117-22. doi: 10.1016/S0093-691X(99)00203-4.
Two different doses of clavulanic acid-potentiated amoxycillin were evaluated for their effect upon semen quality and libido in dogs. There was no significant difference in either parameter between control dogs and dogs treated with clavulanic acid-potentiated amoxycillin at either 12.5 mgkg-1 or 25 mgkg-1 orally twice daily for 28 d. Despite the marked effect of certain antibiotic agents upon spermatogenesis, it appears that clavulanic acid-potentiated amoxycillin can be used in dogs at up to twice the therapeutic dosage recommended by the manufacturer without a deleterious effect upon semen quality.
评估了两种不同剂量的克拉维酸增强阿莫西林对犬精液质量和性欲的影响。对照组犬与口服克拉维酸增强阿莫西林（剂量分别为12.5mg/kg或25mg/kg，每日两次，持续28天）的犬在这两个参数上均无显著差异。尽管某些抗生素对精子发生有显著影响，但克拉维酸增强阿莫西林似乎可以以高达制造商推荐治疗剂量两倍的剂量用于犬，而对精液质量没有有害影响。
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