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Serovars of Mycobacterium avium complex isolated from AIDS and non-AIDS patients in Spain.

作者信息

Torrelles J B, Chatterjee D, Lonca J G, Manterola J M, Ausina V R, Brennan P J

机构信息

Servei de Microbiología, Hospital Universitari Germans Trias i Pujol de Badalona, Facultat de Medicina de la Universitat Autònoma de Barcelona, Spain.

出版信息

J Appl Microbiol. 2000 Feb;88(2):266-79. doi: 10.1046/j.1365-2672.2000.00958.x.

DOI:10.1046/j.1365-2672.2000.00958.x
PMID:10735995
Abstract

Antigen fingerprinting based on surface glycolipid antigens was applied to the epidemiology of clinical isolates of the Mycobacterium avium complex from 128 acquired immunodeficiency syndrome (AIDS) and 31 non-AIDS patients from several different regions of Spain. The application of thin-layer chromatography, gas chromatography-mass spectrometry and monoclonal antibodies, combined with ELISA, allowed a facile identification, differentiation and classification of the isolates. The cumulative results demonstrate that, among the clinical isolates, serovar 4 was predominant in both AIDS (33.6%) and non-AIDS (22.6%) isolates. In general, the results demonstrate geographical as well as disease-related differences in the distribution of Myco. avium complex serovars of clinical importance.

摘要

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