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艾滋病患者体内鸟分枝杆菌复合群的多种血清型

Multiple serovars of Mycobacterium avium complex in patients with AIDS.

作者信息

Julander I, Hoffner S, Petrini B, Ostlund L

机构信息

Department of Infectious Diseases, Huddinge Hospital, Karolinska Institute, Stockholm, Sweden.

出版信息

APMIS. 1996 Apr;104(4):318-20.

PMID:8645472
Abstract

Mycobacterium avium complex (MAC) was isolated and serotyped from 127 samples from 43 HIV-infected patients with disseminated disease in Sweden. Thirteen different serovars were observed. Serovar 6 was the most common, followed by 4, 9 and 11. Serovar 8 was rare. In 22 of the patients the same serovar was found in blood and at other sites. Clinical symptoms and outcome were compared in patients with different serovars. Analysis of patient records revealed no association between clinical picture and any specific serovar. The median survival time after MAC infection was 7 months. Somewhat shorter survival was observed in patients with serovar 4 than in those with serovar 6.

摘要

从瑞典43例患有播散性疾病的HIV感染患者的127份样本中分离出鸟分枝杆菌复合群(MAC)并进行血清分型。观察到13种不同的血清型。血清型6最为常见,其次是4、9和11。血清型8很罕见。在22例患者的血液和其他部位发现了相同的血清型。对不同血清型患者的临床症状和预后进行了比较。对患者记录的分析显示,临床症状与任何特定血清型之间均无关联。MAC感染后的中位生存时间为7个月。血清型4的患者生存时间略短于血清型6的患者。

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