Kuhn F A, Javer A R
Georgia Nasal & Sinus Institute, Savannah, Georgia 31403-3357, USA.
Otolaryngol Clin North Am. 2000 Apr;33(2):419-33. doi: 10.1016/s0030-6665(00)80016-x.
Allergic fungal sinusitis can best be thought of as chronic fungal affectation (not an infection) of the sinuses to which the body's immune system hyperreacts, thereby creating significant inflammation, edema, obstruction, and polyposis. Currently it is felt that allergic fungal sinusitis requires both surgical and medical management. The effectiveness and required duration of the various medical treatments remain unknown and are under active investigation. Both surgical intervention and the use of systemic steroids are recommended in the treatment of allergic fungal sinusitis. Experience with surgical and medical management, follow-up of patients, and proposed treatment protocols are discussed.
变应性真菌性鼻窦炎最好被视为鼻窦的慢性真菌影响(而非感染),机体免疫系统对此产生超敏反应,从而引发显著的炎症、水肿、阻塞及息肉形成。目前认为变应性真菌性鼻窦炎需要手术和药物治疗。各种药物治疗的有效性及所需疗程仍不明确,正在积极研究中。变应性真菌性鼻窦炎的治疗推荐手术干预及全身用类固醇。本文讨论了手术和药物治疗的经验、患者随访情况及建议的治疗方案。