Ravikumar A, Mohanty S, Vatsanath R P, Raghunandhan S
Department of ENT-Head & Neck Surgery, Sriramachandra Medical College & Research Institute, Deemed University, Ramachandra Nagar, Porur, Chennai-600116 Tamil Nadu, India.
Indian J Otolaryngol Head Neck Surg. 2004 Oct;56(4):317-20. doi: 10.1007/BF02974401.
The co-existence of fungal elements in allergic nasal Polyposis, has given rise to a distinct clinical entity known as 'Allergic fungal sinusitis ' (AF'S). Many a time, these fungal elements may not be diagnosed pre-operatively by routine diagnostic nasal endoscopy or CT scan of paranasal sinuses, due to the florid presentation of nasal polyps, which usually obscure the underlying fungal pathology. The diagnosis is often made intra-operatively. The post-operative confirmation of AFS is by histopathology, fungal smear, fungal culture, allergic murin study and fungal specific IgE titres. We report a series often such cases done in our institution, which highlight that AFS should be considered as a differential diagnosis in Sinonasal Polyposis cases, for their effective management.
变应性鼻息肉中真菌成分的共存,引发了一种独特的临床病症,即“变应性真菌性鼻窦炎”(AFS)。很多时候,由于鼻息肉的显著表现通常会掩盖潜在的真菌病理学特征,这些真菌成分在术前通过常规诊断性鼻内镜检查或鼻窦CT扫描可能无法被诊断出来。诊断通常在手术中做出。AFS的术后确诊依靠组织病理学、真菌涂片、真菌培养、变应性小鼠研究以及真菌特异性IgE滴度。我们报告了在我们机构完成的一系列此类病例,这些病例强调,为了有效治疗,在鼻窦息肉病例中应将AFS视为一种鉴别诊断。