Fol M
Katedra Immunologii Instytutu Mikrobiologii i Immunologii, Uniwersytetu Lódzkiego.
Postepy Hig Med Dosw. 1999;53(6):807-22.
Macrophages play a very important role in specific and nonspecific immune response. They are involved in different processes such as phagocytosis and killing of microorganisms, antigen presentation and production of cytokines etc. Their biological activity, ability to cooperate with other cells and to receive signals from extracellular environment are determined by their surface membrane receptors. The paper describes the structure and role of Fc receptors (FcR), adhesion receptors, complement receptors (CR), CD14 (LPS receptors) and receptors for chemotactic agents, present on the surface of macrophages.
巨噬细胞在特异性和非特异性免疫反应中发挥着非常重要的作用。它们参与吞噬和杀灭微生物、抗原呈递以及细胞因子产生等不同过程。它们的生物活性、与其他细胞协作以及从细胞外环境接收信号的能力由其表面膜受体决定。本文描述了巨噬细胞表面存在的Fc受体(FcR)、黏附受体、补体受体(CR)、CD14(LPS受体)和趋化因子受体的结构和作用。