Walker B
Department of Community Health and Family Practice, Howard University Medical Center, Washington, DC 20059, USA.
J Natl Med Assoc. 2000 Mar;92(3):116-24.
A growing number of agents are known to perturb one or more of the interconnected processes of the central nervous system. At the same time, there is an increase in the incidence of neurobehavioral disorders that are confronting clinicians with baffling symptoms and presentations that seem uncommon. Fundamental to the assessment of the environmental-relatedness of the syndromes is a work and exposure history, including information different from that routinely obtained in the clinical setting. Exposure examples are described to suggest the scope of inquiry necessary to differentiate neurotoxic syndromes from nonneurotoxic illness.
已知越来越多的药物会干扰中枢神经系统相互关联的一个或多个过程。与此同时，神经行为障碍的发病率在上升，这些障碍给临床医生带来了令人困惑的症状和表现，这些症状和表现似乎并不常见。评估这些综合征与环境的相关性的基础是工作和接触史，包括与临床常规获取的信息不同的信息。文中描述了接触实例，以表明区分神经毒性综合征和非神经毒性疾病所需的询问范围。
