评估一种新的市售免疫球蛋白M和免疫球蛋白G免疫层析试验用于诊断类鼻疽感染。
Evaluation of a new commercially available immunoglobulin M and immunoglobulin G immunochromatographic test for diagnosis of melioidosis infection.
作者信息
Cuzzubbo A J, Chenthamarakshan V, Vadivelu J, Puthucheary S D, Rowland D, Devine P L
机构信息
PanBio Pty., Ltd., Windsor, Queensland, Australia.
出版信息
J Clin Microbiol. 2000 Apr;38(4):1670-1. doi: 10.1128/JCM.38.4.1670-1671.2000.
Abstract
An immunochromatographic test for the rapid determination of immunoglobulin M (IgM) and IgG antibodies to Burkholderia pseudomallei was evaluated by using sera from bacteriologically confirmed melioidosis patients and high-risk and clinically suspected patients, along with disease control groups. The sensitivities were 100 and 93% for the IgG and IgM tests, respectively, while the specificity was 95% for both assays. The test was rapid and simple to perform, with results obtained in 10 min.
摘要
通过使用来自经细菌学确诊的类鼻疽患者、高危和临床疑似患者的血清以及疾病对照组，对一种用于快速测定抗伯克霍尔德菌假鼻疽免疫球蛋白M（IgM）和IgG抗体的免疫层析试验进行了评估。IgG和IgM检测的灵敏度分别为100%和93%，而两种检测的特异性均为95%。该检测操作快速简便，10分钟即可获得结果。
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