Llewellyn I E, Morris C M, Stanworth S, Heaton D C, Spearing R L
Canterbury Health Laboratories, Christchurch, New Zealand.
Cancer Genet Cytogenet. 2000 Apr 15;118(2):148-50. doi: 10.1016/s0165-4608(99)00134-x.
Trisomy 10 is a rare nonrandom cytogenetic abnormality found in association with acute myeloid leukemia (AML). The hematological and clinical features associated with this finding have not yet been clearly defined. A literature review revealed 13 cases of trisomy 10 in AML, some reported as a minority component of a more comprehensive AML study and therefore lacking a full description of both clinical and hematological features. We present a summary of these reports and add three new cases to the literature.