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甲状腺CT值、碘浓度与组织学变化的相关性

Correlation of CT values, iodine concentration, and histological changes in the thyroid.

作者信息

Imanishi Y, Ehara N, Shinagawa T, Tsujino D, Endoh I, Baba K, Kanemaki Y, Iida S, Hayakawa M, Miyazaki O, Shirakawa K, Nosaka S

机构信息

Department of Radiology, St. Marianna University Yokohama Seibu Hospital, Japan.

出版信息

J Comput Assist Tomogr. 2000 Mar-Apr;24(2):322-6. doi: 10.1097/00004728-200003000-00026.

DOI:10.1097/00004728-200003000-00026
PMID:10752901
Abstract

PURPOSE

We have reported that in the thyroid, there is a linear correlation between iodine concentrations and CT values. However, the slope of the regression line was about three times as large as that in KI solutions. We investigated the factor(s) contributing to the increment of the slope of the regression line in the thyroid.

METHOD

Solutions of NH4I and thyroid hormones were used to investigate the regression line. Thirty-six thyroids were evaluated to investigate the correlation between the iodine concentrations and the area ratio of thyroid follicles, which were measured by preoperative CT and from tissue slices, respectively.

RESULTS

The slopes of the regression lines in the solutions were almost identical to those in KI solutions. In the thyroid, iodine concentrations were logarithmically correlated with the area ratio of follicles.

CONCLUSION

The decrease in CT values not only revealed a decrease of iodine concentration in the thyroid but also represented an increase of follicular cells and/or interstitial structures in the volume ratio secondary to it.

摘要

目的

我们曾报道,在甲状腺中,碘浓度与CT值之间存在线性相关性。然而,回归线的斜率约为碘化钾溶液中的三倍。我们研究了导致甲状腺中回归线斜率增加的因素。

方法

使用碘化铵溶液和甲状腺激素溶液来研究回归线。对36个甲状腺进行评估,以分别通过术前CT和组织切片测量甲状腺滤泡的碘浓度与面积比之间的相关性。

结果

溶液中回归线的斜率与碘化钾溶液中的几乎相同。在甲状腺中,碘浓度与滤泡面积比呈对数相关。

结论

CT值的降低不仅表明甲状腺中碘浓度降低,还代表继发于此的滤泡细胞和/或间质结构体积比增加。

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