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Using anticoagulation or aspirin to prevent stroke. Research was methodologically flawed.

作者信息

Ellis S J, Hans R

出版信息

BMJ. 2000 Apr 8;320(7240):1008-9; author reply 1010-1. doi: 10.1136/bmj.320.7240.1008.

DOI:10.1136/bmj.320.7240.1008
PMID:10753166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1117881/
Abstract
摘要

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1
Using anticoagulation or aspirin to prevent stroke. Research was methodologically flawed.使用抗凝剂或阿司匹林预防中风。研究在方法上存在缺陷。
BMJ. 2000 Apr 8;320(7240):1008-9; author reply 1010-1. doi: 10.1136/bmj.320.7240.1008.
2
Using anticoagulation or aspirin to prevent stroke. Study does not have the power to show that aspirin is as good as anticoagulation.使用抗凝剂或阿司匹林预防中风。该研究没有足够的说服力表明阿司匹林与抗凝剂效果相当。
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Stroke. 2002 Jun;33(6):1723-6. doi: 10.1161/01.str.0000016922.22707.27.
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Ximelagatran or warfarin in atrial fibrillation?希美加群与华法林用于治疗房颤？
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Using aspirin to prevent stroke.使用阿司匹林预防中风。
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引用本文的文献

1
Long term anticoagulation or antiplatelet treatment. Only warfarin has been shown to reduce stroke risk in patients with atrial fibrillation.长期抗凝或抗血小板治疗。仅华法林已被证明可降低房颤患者的中风风险。
BMJ. 2001 Jul 28;323(7306):233; author reply 235-6.
2
Care is required with cost effectiveness approach.采用成本效益方法时需要谨慎。
BMJ. 2000 Aug 12;321(7258):449.

本文引用的文献

1
Atrial fibrillation and thromboembolism: a decade of progress in stroke prevention.心房颤动与血栓栓塞：卒中预防十年进展
Ann Intern Med. 1999 Nov 2;131(9):688-95. doi: 10.7326/0003-4819-131-9-199911020-00010.
2
Use of antithrombotic measures for stroke prevention in atrial fibrillation.使用抗血栓措施预防心房颤动中的卒中
Heart. 1999 Nov;82(5):570-4. doi: 10.1136/hrt.82.5.570.
3
Primary prevention of arterial thromboembolism in non-rheumatic atrial fibrillation in primary care: randomised controlled trial comparing two intensities of coumarin with aspirin.基层医疗中对非风湿性心房颤动患者进行动脉血栓栓塞的一级预防：比较两种强度香豆素与阿司匹林的随机对照试验
BMJ. 1999 Oct 9;319(7215):958-64. doi: 10.1136/bmj.319.7215.958.
4
Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: a meta-analysis.预防心房颤动患者中风的抗栓治疗：一项荟萃分析。
Ann Intern Med. 1999 Oct 5;131(7):492-501. doi: 10.7326/0003-4819-131-7-199910050-00003.
5
Bleeding during warfarin and aspirin therapy in patients with atrial fibrillation: the AFASAK 2 study. Atrial Fibrillation Aspirin and Anticoagulation.心房颤动患者华法林与阿司匹林联合治疗期间的出血情况：AFASAK 2研究。心房颤动、阿司匹林与抗凝治疗。
Arch Intern Med. 1999 Jun 28;159(12):1322-8. doi: 10.1001/archinte.159.12.1322.
6
Antithrombotic therapy in atrial fibrillation.心房颤动的抗栓治疗
Chest. 1998 Nov;114(5 Suppl):579S-589S. doi: 10.1378/chest.114.5_supplement.579s.
7
Prevalence of atrial fibrillation and eligibility for anticoagulants in the community.社区中房颤的患病率及抗凝治疗的适用性
Lancet. 1998 Oct 10;352(9135):1167-71. doi: 10.1016/S0140-6736(98)01401-9.
8
Effectiveness of fixed minidose warfarin in the prevention of thromboembolism and vascular death in nonrheumatic atrial fibrillation.固定小剂量华法林预防非风湿性心房颤动患者血栓栓塞及血管性死亡的有效性
Am J Cardiol. 1998 Aug 15;82(4):433-7. doi: 10.1016/s0002-9149(98)00357-9.
9
A survey of atrial fibrillation in general practice: the West Birmingham Atrial Fibrillation Project.一项全科医疗中房颤的调查：西米德兰兹郡房颤项目
Br J Gen Pract. 1997 May;47(418):285-9.
10
The efficacy of aspirin in patients with atrial fibrillation. Analysis of pooled data from 3 randomized trials. The Atrial Fibrillation Investigators.阿司匹林对心房颤动患者的疗效。来自3项随机试验的汇总数据分析。心房颤动研究人员。
Arch Intern Med. 1997 Jun 9;157(11):1237-40.