Edmonds D K
Queen Charlotte's and Chelsea Hospital, London, UK.
Baillieres Best Pract Res Clin Obstet Gynaecol. 1999 Jun;13(2):239-49. doi: 10.1053/beog.1999.0020.
Dysfunctional uterine bleeding in adolescence is usually not a pathological process but a physiological adjustment in the achievement of normal reproductive status. The source of the problem in the vast majority of patients lies in the development of an intact hypothalamo-pituitary ovarian axis which exhibits normal pulsatile gonadotrophin release. The achievement of this in point usually resolves the dysfunctional bleeding problem. Management of these problems is dependent on the clinical impact of blood loss and only requires medication when menstrual loss needs to be controlled. Special circumstances, such as mentally retarded children, require special attention in order to fulfil a number of clinical difficulties and almost always require medical intervention.
青春期功能失调性子宫出血通常不是一个病理过程，而是在实现正常生殖状态过程中的一种生理调节。绝大多数患者的问题根源在于完整的下丘脑-垂体-卵巢轴的发育，该轴表现出正常的促性腺激素脉冲式释放。达到这一点通常就能解决功能失调性出血问题。这些问题的处理取决于失血的临床影响，只有在需要控制月经失血时才需要用药。特殊情况，如智障儿童，需要特别关注以解决一些临床难题，而且几乎总是需要医学干预。
