非隐形眼镜佩戴者中由铜绿假单胞菌引起的严重硬化性角膜炎。
Severe sclerokeratitis due to Pseudomonas aeruginosa in noncontact-lens wearers.
作者信息
Radford R, Brahma A, Armstrong M, Tullo A B
机构信息
Department of Ophthalmology, Royal Eye Hospital, Manchester, UK.
出版信息
Eye (Lond). 2000 Feb;14 ( Pt 1):3-7. doi: 10.1038/eye.2000.2.
PURPOSE
To review the clinical presentation, treatment and outcome in four cases of severe anterior segment infection by Pseudomonas aeruginosa unrelated to contact lens wear.
METHODS
Four cases presenting over an 18 month period were reviewed.
RESULTS
The cases had variable presenting features and outcomes. Complications such as persistent infection, corneal thinning and phthisis bulbi were noted. Possible factors influencing adherence and tissue disruption are discussed.
CONCLUSIONS
Suspicion of infection by P. aeruginosa and prompt isolation of the organism is needed early in the course of disease. Intensive and prolonged treatment with parenteral and topical antibiotics combined with judicious use of topical steroid gives the best chance of a favourable outcome.
目的
回顾4例与隐形眼镜佩戴无关的铜绿假单胞菌引起的严重眼前段感染的临床表现、治疗及预后。
方法
回顾18个月期间出现的4例病例。
结果
这些病例有不同的表现特征和预后。记录到诸如持续感染、角膜变薄和眼球痨等并发症。讨论了影响细菌黏附和组织破坏的可能因素。
结论
在疾病过程早期需要怀疑铜绿假单胞菌感染并及时分离出该病原体。胃肠外和局部使用抗生素进行强化和长期治疗，同时明智地使用局部类固醇，可提供获得良好预后的最佳机会。
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