催乳素分泌与免疫系统。

Prolactin secretion and the immune system.

作者信息

Luca I C

机构信息

Disciplina de Histologie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 1997 Jul-Dec;101(3-4):56-9.

PMID:10756771

Abstract

Prolactin receptors were identified on the membranes of lymphocytes have been demonstrated to secrete prolactin. The decrease, as well as the increase of the prolactin level in the plasma are responsible for immune disorders. Prolactin dysfunction has been described in some autoimmune diseases, such as systemic lupus erythematosus, immune arthritis, uveitis, experimental allergic encephalomyelitis and thyroid disease. The normal prolactin secretion is trophic for the lymphocytes, while the high and also the low levels of prolactin may play an immunosuppressive role.

摘要

已证实在分泌催乳素的淋巴细胞细胞膜上存在催乳素受体。血浆中催乳素水平的降低以及升高均会导致免疫紊乱。在一些自身免疫性疾病中，如系统性红斑狼疮、免疫性关节炎、葡萄膜炎、实验性变应性脑脊髓炎和甲状腺疾病，均有催乳素功能障碍的描述。正常的催乳素分泌对淋巴细胞具有营养作用，而催乳素水平过高和过低均可能发挥免疫抑制作用。