Ferrara N, Baldi G, Di Marino M P, Bellucci G, Baldi A
IV Cattedra di Anatomia ed Istologia Pathologica, II Università di Napoli, Italy.
In Vivo. 2000 Jan-Feb;14(1):105-7.
Atypical fibroxanthoma (AF) is generally considered as a low grade superficial variant of fibrohistiocytic neoplasm. In this report we present an unusual variant of this neoplasm arising from actinic damaged skin of an elderly individual. The case was characterized by numerous multinucleated osteoclast-like giant cells uniformly scattered through a pleomorfic cellular proliferation. The osteoclasts giant cell observed represent multinucleated histiocytes rather than true osteoclasts.