Tomaszewski M M, Lupton G P
Department of Dermatopathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000, USA.
Am J Surg Pathol. 1997 Feb;21(2):213-8. doi: 10.1097/00000478-199702000-00012.
We report three cases of an unusual variant of atypical fibroxanthoma with numerous multinucleated osteoclast-like giant cells. Histologically, the lesions were composed of uniformly dispersed multinucleated osteoclast-like giant cells within a pleomorphic cellular proliferation with microscopic and histochemical features of atypical fibroxanthoma. Multinucleated osteoclast-like giant cells, however, stained with KP-1, a macrophage-associated antigen only. These cells are not necessarily an integral part of the tumor and may represent a reactive histiocytic component.
我们报告了三例具有大量多核破骨细胞样巨细胞的非典型纤维黄色瘤的不寻常变体。组织学上，病变由均匀分散在多形性细胞增殖中的多核破骨细胞样巨细胞组成，具有非典型纤维黄色瘤的微观和组织化学特征。然而，多核破骨细胞样巨细胞仅用巨噬细胞相关抗原KP-1染色。这些细胞不一定是肿瘤的组成部分，可能代表反应性组织细胞成分。
