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使用阴道抗真菌药物进行自我药疗:医生的经验与女性的用药模式。

Self-medication with vaginal antifungal drugs: physicians' experiences and women's utilization patterns.

作者信息

Sihvo S, Ahonen R, Mikander H, Hemminki E

机构信息

Stakes (National Research and Development Centre for Welfare and Health), POB 220, 00531 Helsinki, Finland.

出版信息

Fam Pract. 2000 Apr;17(2):145-9. doi: 10.1093/fampra/17.2.145.

DOI:10.1093/fampra/17.2.145
PMID:10758077
Abstract

BACKGROUND

In many countries, vaginal antifungal drugs have been released on over-the-counter (OTC) markets, yet little is known about women's management of their symptoms.

OBJECTIVES

The aim of this study was to judge the appropriateness of self-medication with vaginal antifungal drugs by examining utilization patterns and physicians' experiences of women's self-medication.

METHODS

An anonymous questionnaire survey was carried out in 20 pharmacies in Finland of women buying OTC vaginal antifungal drugs in 1997. Out of the 453 questionnaires distributed, 299 (66%) were returned. A survey of a random sample of gynaecologists (n = 169) and specialists in general practice (n = 288) was carried out in 1996. The response rate was 77%.

RESULTS

Nearly all women had used vaginal antifungal drugs previously, 49% during the previous 6 months. Most women did not report any difficulties with treatment, but 44% of women used the drug against recommendations. Half of the women had symptoms that are more likely to be related to infections other than Candida. Physicians had observed several disadvantages of self-treatment, with unnecessary use and use for the wrong indications being the most often reported. In all, 31% of gynaecologists and 16% of GPs reported that these adverse events had been clinically significant, with delay in the treatment of other infections being the most common problem.

CONCLUSION

The results raise concerns about inappropriate use and women's ability to self-diagnose correctly. Because vaginal antifungal drugs are likely to remain on OTC markets, two ways to address these concerns are for physicians and pharmacy personnel to provide spontaneous information and to have more informative advertisements on vaginal antifungal drugs.

摘要

背景

在许多国家,阴道抗真菌药物已投放非处方药(OTC)市场,但对于女性对自身症状的处理情况知之甚少。

目的

本研究旨在通过检查使用模式以及医生对女性自我用药的经验,判断阴道抗真菌药物自我用药的合理性。

方法

1997年在芬兰的20家药店对购买非处方阴道抗真菌药物的女性进行了匿名问卷调查。在分发的453份问卷中,299份(66%)被收回。1996年对妇科医生(n = 169)和全科医生(n = 288)的随机样本进行了调查。回复率为77%。

结果

几乎所有女性之前都使用过阴道抗真菌药物,49%在过去6个月内使用过。大多数女性没有报告治疗有任何困难,但44%的女性用药不符合推荐。一半女性的症状更可能与念珠菌以外的感染有关。医生观察到自我治疗存在几个弊端,最常报告的是不必要的使用和用于错误的适应症。总体而言,31%的妇科医生和16%的全科医生报告称这些不良事件具有临床意义,治疗其他感染的延迟是最常见的问题。

结论

结果引发了对不当使用以及女性正确自我诊断能力的担忧。由于阴道抗真菌药物可能会继续留在非处方药市场,解决这些担忧的两种方法是医生和药房工作人员提供自发信息,并制作关于阴道抗真菌药物的更具信息性的广告。

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