Lee Chun-Hsien, Chang Fong-Ching, Hsu Sheng-Der, Chi Hsueh-Yun, Huang Li-Jung, Yeh Ming-Kung
Department of Health Promotion and Health Education, National Taiwan Normal University, Taipei, Taiwan, ROC.
Department of Pharmacy Practice, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
PLoS One. 2017 Dec 14;12(12):e0189199. doi: 10.1371/journal.pone.0189199. eCollection 2017.
While self-medication is common, inappropriate self-medication has potential risks. This study assesses inappropriate self-medication among adolescents and examines the relationships among medication literacy, substance use, and inappropriate self-medication.
In 2016, a national representative sample of 6,226 students from 99 primary, middle, and high schools completed an online self-administered questionnaire. Multiple logistic regression analysis was used to examine factors related to inappropriate self-medication.
The prevalence of self-medication in the past year among the adolescents surveyed was 45.8%, and the most frequently reported drugs for self-medication included nonsteroidal anti-inflammatory drugs or pain relievers (prevalence = 31.1%), cold or cough medicines (prevalence = 21.6%), analgesics (prevalence = 19.3%), and antacids (prevalence = 17.3%). Of the participants who practiced self-medication, the prevalence of inappropriate self-medication behaviors included not reading drug labels or instructions (10.1%), using excessive dosages (21.6%), and using prescription and nonprescription medicine simultaneously without advice from a health provider (polypharmacy) (30.3%). The results of multiple logistic regression analysis showed that after controlling for school level, gender, and chronic diseases, the participants with lower medication knowledge, lower self-efficacy, lower medication literacy, and who consumed tobacco or alcohol were more likely to engage in inappropriate self-medication.
Lower medication literacy and substance use were associated with inappropriate self-medication among adolescents.
虽然自我药疗很常见，但不恰当的自我药疗存在潜在风险。本研究评估青少年中的不恰当自我药疗情况，并探讨用药知识、物质使用与不恰当自我药疗之间的关系。
2016年，来自99所小学、初中和高中的6226名学生组成的全国代表性样本完成了一份在线自填问卷。采用多元逻辑回归分析来检验与不恰当自我药疗相关的因素。
在接受调查的青少年中，过去一年自我药疗的患病率为45.8%，最常报告的自我药疗药物包括非甾体抗炎药或止痛药（患病率=31.1%）、感冒药或咳嗽药（患病率=21.6%）、镇痛药（患病率=19.3%）和抗酸剂（患病率=17.3%）。在进行自我药疗的参与者中，不恰当自我药疗行为的患病率包括不阅读药品标签或说明书（10.1%）、使用过量剂量（21.6%）以及在没有医疗服务提供者建议的情况下同时使用处方药和非处方药（多药联用）（30.3%）。多元逻辑回归分析结果显示，在控制了学校水平、性别和慢性病因素后，用药知识较低、自我效能较低、用药素养较低以及吸烟或饮酒的参与者更有可能进行不恰当的自我药疗。
较低的用药素养和物质使用与青少年不恰当的自我药疗有关。
