Pradalier A, Vincent D
Service de médecine interne IV, centre d'allergie de l'Ouest parisien, hôpital Louis-Mourier, Colombes, France.
Rev Med Interne. 2000 Mar;21 Suppl 1:75s-82s. doi: 10.1016/s0248-8663(00)88728-7.
The paper describes the clinical characteristics of patients with aspirin-induced asthma and/or urticaria, angioedema, shock, the results of the challenge tests and the evolution of this disease.
The authors present the different arguments supporting the physiopathological mechanisms from genetics to the inhibition of cyclooxugenase or the leukotriene hypothesis.
Finally, they recall the methodology to be used for a good clinical practice on this controversial field of research.
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