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梅尼埃病患者的难治性良性阵发性位置性眩晕

Intractable benign paroxysmal positional vertigo in patients with Meniere's disease.

作者信息

Gross E M, Ress B D, Viirre E S, Nelson J R, Harris J P

机构信息

Division of Head and Neck Surgery, University of California-San Diego, USA.

出版信息

Laryngoscope. 2000 Apr;110(4):655-9. doi: 10.1097/00005537-200004000-00022.

Abstract

OBJECTIVE

To provide a detailed description of the coexistence of benign paroxysmal positional vertigo (BPPV) and Meniere's disease in individuals and to offer a possible mechanism that explains the findings in these patients.

STUDY DESIGN

Retrospective.

METHODS

Chart review.

RESULTS

Of 162 patients diagnosed with Meniere's disease between January 1998 and January 1999, 9 were found to have both "definite" Meniere's disease and "certain" BPPV. Meniere's symptoms preceded the onset of BPPV in all of our patients. Seven of the 9 patients were female. Except for one patient who experienced BPPV bilaterally, BPPV was limited to the same ear as the Meniere's disease. All patients presented with intractable BPPV that did not respond completely to otolith repositioning procedures. A detailed description of five patients is presented.

CONCLUSION

Our data, in conjunction with that of others, suggest that Meniere's disease may predispose patients to intractable BPPV. Hydropically induced damage to the maculae of the utricle and saccule or partial obstruction of the membranous labyrinth may be possible mechanisms that explain the coexistence of Meniere's disease and BPPV.

摘要

目的

详细描述个体中良性阵发性位置性眩晕(BPPV)与梅尼埃病并存的情况,并提供一种可能解释这些患者相关发现的机制。

研究设计

回顾性研究。

方法

病历回顾。

结果

在1998年1月至1999年1月期间诊断为梅尼埃病的162例患者中,有9例被发现同时患有“明确的”梅尼埃病和“肯定的”BPPV。在我们所有患者中,梅尼埃病症状先于BPPV发作。9例患者中有7例为女性。除1例双侧出现BPPV的患者外,BPPV局限于与梅尼埃病同侧的耳朵。所有患者均表现为顽固性BPPV,耳石复位程序不能使其完全缓解。现对5例患者进行详细描述。

结论

我们的数据以及其他研究的数据表明,梅尼埃病可能使患者易患顽固性BPPV。内淋巴积水导致的椭圆囊和球囊斑损伤或膜迷路部分梗阻可能是解释梅尼埃病与BPPV并存的潜在机制。

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