Black J
College of Nursing, University of Nebraska Medical Center, Omaha, USA.
Plast Surg Nurs. 1999 Fall;19(3):143-7.
Melanoma is the malignant tumor deriving from melanocytes through malignant transformation. Melanocytes originate at the neuro-ectodermal crest (the tissue matrix for the brain and medullary spine). These cells migrate during the early fetal period into the skin and settle within the epidermis, becoming part of the skin structure. Melanocytes differ from the other skin cells however; they have a neuro-ectodermal origin, the potential of migrating, and the functional capacity of nerve cell units.
黑色素瘤是黑色素细胞发生恶性转化而形成的恶性肿瘤。黑色素细胞起源于神经外胚层嵴（脑和脊髓的组织基质）。这些细胞在胎儿早期迁移到皮肤并定居于表皮内，成为皮肤结构的一部分。然而，黑色素细胞与其他皮肤细胞不同；它们起源于神经外胚层，具有迁移的潜能以及神经细胞单位的功能能力。
