Punnose J, Agarwal M M, Premchandran J S
Department of Medicine, Al Ain Hospital, Al Ain, United Arab Emirates.
Am J Med Sci. 2000 Apr;319(4):261-4. doi: 10.1097/00000441-200004000-00012.
Pituitary apoplexy in a 38-year-old male patient with acromegaly who presented with pericardial effusion, anterior pituitary dysfunction, and diabetes insipidus is described. With corticosteroid therapy, there was good initial recovery of pituitary function and regression of pericardial effusion. On withdrawal of corticosteroids, he developed painless thyroiditis, with transient thyrotoxicosis. Subsequently, the pituitary function tests remained normal for a year, but later he gradually developed hypogonadotropic hypogonadism, hypocortisolism, growth hormone deficiency, and progressive pituitary atrophy, resulting in empty sella syndrome.
描述了一名38岁肢端肥大症男性患者发生垂体卒中，伴有心包积液、垂体前叶功能障碍和尿崩症。经皮质类固醇治疗后，垂体功能最初恢复良好，心包积液消退。停用皮质类固醇后，他发生了无痛性甲状腺炎，并伴有短暂甲状腺毒症。随后，垂体功能测试在一年内保持正常，但后来他逐渐发展为低促性腺激素性性腺功能减退、皮质醇缺乏、生长激素缺乏和进行性垂体萎缩，导致空蝶鞍综合征。
