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本文引用的文献

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Strategies and tools for the control/elimination of lymphatic filariasis.控制/消除淋巴丝虫病的策略与工具
Bull World Health Organ. 1997;75(6):491-503.
2
Infectivity and normal development of third stage Brugia malayi maintained in vitro.体外培养的马来布鲁线虫第三期幼虫的感染性及正常发育
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Infection of IL-4-deficient mice with the parasitic nematode Brugia malayi demonstrates that host resistance is not dependent on a T helper 2-dominated immune response.用寄生线虫马来布鲁线虫感染白细胞介素-4缺陷小鼠，结果表明宿主抗性并不依赖于以辅助性T细胞2为主导的免疫反应。
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The regulation of immunity to Leishmania major.对硕大利什曼原虫免疫的调节
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γ干扰素和白细胞介素-4在宿主抵御马来布鲁线虫这种人体丝虫寄生虫中的作用。

Role of gamma interferon and interleukin-4 in host defense against the human filarial parasite Brugia malayi.

作者信息

Babu S, Ganley L M, Klei T R, Shultz L D, Rajan T V

机构信息

Department of Pathology, University of Connecticut Health Center, Farmington, Connecticut 06030-3105, USA.

出版信息

Infect Immun. 2000 May;68(5):3034-5. doi: 10.1128/IAI.68.5.3034-3035.2000.

DOI:10.1128/IAI.68.5.3034-3035.2000
PMID:10769010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC97525/
Abstract

We have investigated the roles of gamma interferon (IFN-gamma) and interleukin-4 (IL-4) in host defense against Brugia malayi. Our data suggest that the lack of either IFN-gamma or IL-4 prolongs the time required to achieve sterile immunity, suggesting that both canonical type 1 and type 2 responses are involved in the clearance of infection.

摘要

我们研究了γ干扰素（IFN-γ）和白细胞介素-4（IL-4）在宿主抵御马来布鲁线虫中的作用。我们的数据表明，缺乏IFN-γ或IL-4都会延长实现无菌免疫所需的时间，这表明典型的1型和2型免疫反应都参与了感染的清除过程。