重型地中海贫血患者的血清免疫球蛋白、IgG亚类、同种血凝素和补体3水平。
Serum immunoglobulins, IgG subclasses, isohemagglutinins and complement-3 levels in patients with thalassemia major.
作者信息
Vergin C, Kutukculer N, Cetingul N, Nisli G, Caglayan S, Oztop S
机构信息
Department of Pediatrics, Faculty of Medicine, Ege University, Izmir, Turkey.
出版信息
Indian J Pediatr. 1997 Mar-Apr;64(2):215-9. doi: 10.1007/BF02752450.
Serum IgG, IgM, IgA, IgG subclasses (IgG1, G2, G3, G4), isohemagglutinins and complement-3 concentrations were measured in 23 beta-thalassemic patients suffering from recurrent infections. No significant abnormalities were found in these humoral immunity investigations, both in splenectomized and non-splenectomized patients. On the other hand, iron overload or repeated blood transfusions were not found to down-regulate the humoral immune system of thalassemic patients.
对23例患有反复感染的β地中海贫血患者的血清IgG、IgM、IgA、IgG亚类（IgG1、G2、G3、G4）、同种血凝素和补体3浓度进行了检测。在这些体液免疫检查中，无论是脾切除患者还是未行脾切除的患者均未发现明显异常。另一方面，未发现铁过载或反复输血会下调地中海贫血患者的体液免疫系统。
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