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儿童打鼾与阻塞性睡眠呼吸暂停:一项为期6个月的随访研究。

Snoring and obstructive sleep apnea in children: a 6-month follow-up study.

作者信息

Nieminen P, Tolonen U, Löppönen H

机构信息

Department of Otorhinolaryngology, Oulu University Hospital, Finland.

出版信息

Arch Otolaryngol Head Neck Surg. 2000 Apr;126(4):481-6. doi: 10.1001/archotol.126.4.481.

DOI:10.1001/archotol.126.4.481
PMID:10772301
Abstract

BACKGROUND

Snoring children may present symptoms suggestive of obstructive sleep apnea syndrome (OSAS). Different and controversial methods to establish the diagnosis and to choose the treatment modalities have been proposed.

OBJECTIVES

To study children with symptoms raising the suspicion of OSAS with overnight polysomnography (PSG). To evaluate the efficacy of adenotonsillectomy as treatment of pediatric OSAS and to elucidate the natural history of OSAS and primary snoring.

DESIGN

A controlled, prospective, nonrandomized clinical trial.

SETTING

Academic medical center.

SUBJECTS

Fifty-eight snoring but otherwise healthy children aged 3 to 10 years with symptoms suggestive of OSAS underwent PSG twice, 6 months apart. Thirty healthy children served as controls.

RESULTS

Twenty-seven children had OSAS with an obstructive apnea/hypopnea index greater than 1, while 31 had primary snoring. There were statistical differences in the symptoms and signs among the 3 study groups. Adenotonsillectomy was curative in the 21 children with OSAS who were operated on. Obstructive apneas and hypopneas in the healthy, nonsnoring children were almost nonexistent in this study.

CONCLUSIONS

Half of the children or fewer with symptoms suggestive of OSAS actually had the condition. Clinical symptoms may raise the suspicion, but it is not possible to establish the diagnosis without PSG. Because snoring and obstructive symptoms may resolve over time, a normal PSG finding may help the clinician decide on an observation period. Adenotonsillectomy is curative in most cases of pediatric OSAS. Obstructive symptoms may continue after adenoidectomy alone.

摘要

背景

打鼾儿童可能出现提示阻塞性睡眠呼吸暂停综合征(OSAS)的症状。已经提出了不同且有争议的方法来确立诊断和选择治疗方式。

目的

采用整夜多导睡眠图(PSG)研究有提示OSAS症状的儿童。评估腺样体扁桃体切除术治疗小儿OSAS的疗效,并阐明OSAS和原发性打鼾的自然病程。

设计

一项对照、前瞻性、非随机临床试验。

地点

学术医疗中心。

研究对象

58名年龄在3至10岁、打鼾但其他方面健康且有提示OSAS症状的儿童接受了两次间隔6个月的PSG检查。30名健康儿童作为对照。

结果

27名儿童患有OSAS,阻塞性呼吸暂停/低通气指数大于1,而31名儿童为原发性打鼾。3个研究组在症状和体征方面存在统计学差异。接受手术的21名OSAS儿童经腺样体扁桃体切除术后治愈。在本研究中,健康、不打鼾儿童几乎不存在阻塞性呼吸暂停和低通气。

结论

有提示OSAS症状的儿童中半数或更少实际患有该病。临床症状可能引起怀疑,但没有PSG检查无法确立诊断。由于打鼾和阻塞性症状可能随时间缓解,PSG检查结果正常可能有助于临床医生决定观察期。腺样体扁桃体切除术对大多数小儿OSAS病例有效。单独行腺样体切除术后阻塞性症状可能持续存在。

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