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打鼾儿童:预测睡眠呼吸暂停的因素。

Snoring children: factors predicting sleep apnea.

作者信息

Nieminen P, Tolonen U, Löppönen H, Löppönen T, Luotonen J, Jokinen K

机构信息

Department of Otolaryngology, Oulu University Hospital, Finland.

出版信息

Acta Otolaryngol Suppl. 1997;529:190-4. doi: 10.3109/00016489709124119.

DOI:10.3109/00016489709124119
PMID:9288307
Abstract

Many snoring children present obstructive symptoms according to their parents. The seriousness of the symptoms and the possibility of the obstructive sleep apnea syndrome (OSAS) in these children may be difficult to judge on the basis of the clinical findings and the patient's history only. In order to evaluate snoring children's relative risk (RR) to have OSAS, their symptoms and signs, as reported by the parents, and clinical findings were compared with the results of overnight polysomnography (PSG). An obstructive apnea index (AI) > or = 1 in PSG was regarded as the criterion for OSAS. The mean AI was 1.55 (range 0-15), and 29 children had a pathological AI, while 49 had a normal PSG recording. Apneic episodes every night detected by the parents was the most important single risk factor for OSAS (RR 3.6, 95% confidence interval (CI) 1.7-7.7). The RR ratio decreased when apneas appeared less frequently, but any detected apnea was still a single risk factor (RR 1.4, CI 1.2-1.8). The other risk factors of night-time symptoms were constant snoring (RR 1.5, CI 1.0-2.1) and restless sleep (RR 2.1, CI 1.1-4.0). Of the daytime symptoms, absence of excessive sleepiness was a protective factor against OSAS (RR 0.3, CI 0.1-1.0). Previous adenoidectomy was found to be a risk factor (RR 1.7, CI 1.1-2.7), as was tonsillar enlargement (RR 1.4, CI 1.1-1.8). These two findings suggest that the epipharyngeal space does not play a central role in the development of OSAS in children. OSAS cannot be reliably diagnosed without PSG, which is the most important examination for snoring children with obstructive symptoms. For clinical decisions, the consideration of risk factors is essential.

摘要

许多家长反映孩子存在打鼾及阻塞性症状。仅依据临床表现和病史可能难以判断这些症状的严重程度以及孩子患阻塞性睡眠呼吸暂停综合征(OSAS)的可能性。为了评估打鼾儿童患OSAS的相对风险(RR),将家长报告的孩子症状和体征以及临床检查结果与夜间多导睡眠图(PSG)结果进行比较。PSG中阻塞性呼吸暂停指数(AI)≥1被视为OSAS的标准。平均AI为1.55(范围0 - 15),29名儿童的AI呈病理性,而49名儿童的PSG记录正常。家长每晚检测到的呼吸暂停发作是OSAS最重要的单一风险因素(RR 3.6,95%置信区间(CI)1.7 - 7.7)。当呼吸暂停发作频率降低时,RR比值下降,但任何检测到的呼吸暂停仍是单一风险因素(RR 1.4,CI 1.2 - 1.8)。夜间症状的其他风险因素包括持续打鼾(RR 1.5,CI 1.0 - 2.1)和睡眠不安(RR 2.1,CI 1.1 - 4.0)。在白天症状中,无过度嗜睡是预防OSAS的保护因素(RR 0.3,CI 0.1 - 1.0)。既往腺样体切除术被发现是一个风险因素(RR 1.7,CI 1.1 - 2.7),扁桃体肿大也是如此(RR 1.4,CI 1.1 - 1.8)。这两个发现表明咽上间隙在儿童OSAS的发生发展中并不起核心作用。没有PSG就无法可靠地诊断OSAS,PSG是对有阻塞性症状的打鼾儿童最重要的检查。对于临床决策而言,考虑风险因素至关重要。

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