Hatton R C
Drug Information and Pharmacy Resource Center, Shands at the University of Florida, Gainesville 32610, USA.
Ann Pharmacother. 2000 Apr;34(4):522-5. doi: 10.1345/aph.19216.
To evaluate the role of bismuth subgallate-epinephrine (BSE) paste as a hemostatic in adenotonsillectomies.
MEDLINE (January 1966-October 1999) and Current Contents (January 1997-October 1999) were searched, using bismuth subgallate, adenoidectomy, tonsillectomy, and adenotonsillectomy as search terms. A citation search was performed using Science Citation Index (January 1977-October 1999).
Adenotonsillectomies are common procedures; although there are few complications, hemorrhage is a concern. Bismuth subgallate has historically been used as an astringent and hemostatic. An evaluation of studies of bismuth subgallate and BSE paste was conducted.
There is minimal evidence to support this practice, but data suggest that epinephrine may be the active ingredient in BSE paste. BSE paste is inexpensive, poses little risk, and may decrease postoperative bleeding; therefore, it may be a reasonable hemostatic agent.
评估次没食子酸铋 - 肾上腺素(BSE)糊剂在腺样体扁桃体切除术中作为止血剂的作用。
检索了MEDLINE(1966年1月至1999年10月)和《现刊目次》(1997年1月至1999年10月),使用次没食子酸铋、腺样体切除术、扁桃体切除术和腺样体扁桃体切除术作为检索词。使用《科学引文索引》(1977年1月至1999年10月)进行了引文检索。
腺样体扁桃体切除术是常见手术;虽然并发症较少,但出血是一个令人担忧的问题。次没食子酸铋历来被用作收敛剂和止血剂。对次没食子酸铋和BSE糊剂的研究进行了评估。
支持这种做法的证据很少,但数据表明肾上腺素可能是BSE糊剂中的活性成分。BSE糊剂价格低廉,风险小,可能会减少术后出血;因此,它可能是一种合理的止血剂。