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次没食子酸铋——其在扁桃体切除术中的作用。

Bismuth subgallate--its role in tonsillectomy.

作者信息

Fenton J E, Blayney A W, O'Dwyer T P

机构信息

Department of Otolaryngology, Temple Street Children's Hospital, Dublin.

出版信息

J Laryngol Otol. 1995 Mar;109(3):203-5. doi: 10.1017/s002221510012969x.

Abstract

There have been many attempts at identifying substances and describing methods that would assist the surgeon and be of benefit to the patient undergoing a tonsillectomy. The use of bismuth subgallate as a haemostatic adjunct during tonsillectomy has only been described previously in retrospective studies. A controlled prospective randomized trial of 100 paediatric patients, in which 50 patients had a tonsillectomy performed using bismuth subgallate as a haemostatic agent and in which the remainder did not have any associated haemostatic substance, is presented here. Data on 72 patients was analysed, 39 patients belonging to the bismuth subgallate group and the remaining 33 to the control group. The time for haemostasis was three to 18 (mean 7.8) minutes in the bismuth group. It was four to 16 (mean 9.9) minutes in the non-bismuth group. These figures are statistically significant. The range of ties used in the bismuth group was none to three (mean 1.5) ties and one to seven (mean 3.4) ties in the non-bismuth group. These figures are also statistically significant. The remainder of the recorded parameters did not differ significantly. It was found that bismuth subgallate/adrenaline paste decreases operating time by significantly reducing the haemostasis time and the number of ties required but does not decrease post-operative morbidity.

摘要

人们曾多次尝试识别有助于外科医生并对接受扁桃体切除术的患者有益的物质和描述方法。在扁桃体切除术中使用次没食子酸铋作为止血辅助剂,此前仅在回顾性研究中有过描述。本文介绍了一项针对100名儿科患者的对照前瞻性随机试验,其中50名患者在扁桃体切除术中使用次没食子酸铋作为止血剂,其余患者未使用任何相关止血物质。分析了72名患者的数据,39名患者属于次没食子酸铋组,其余33名属于对照组。铋组的止血时间为3至18分钟(平均7.8分钟)。非铋组为4至16分钟(平均9.9分钟)。这些数字具有统计学意义。铋组使用结扎线的数量范围为0至3根(平均1.5根),非铋组为1至7根(平均3.4根)。这些数字也具有统计学意义。记录的其余参数没有显著差异。结果发现,次没食子酸铋/肾上腺素糊剂通过显著缩短止血时间和所需结扎线数量,减少了手术时间,但并未降低术后发病率。

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