Glémarec J, Guillot P, Laborie Y, Berthelot J M, Prost A, Maugars Y
Rheumatology Department, Hôtel-Dieu Teaching Hospital, Nantes, France.
Joint Bone Spine. 2000 Jan;67(1):54-61.
To evaluate the overall efficacy in various disorders of glucocorticoid injection into the lateral atlantoaxial joints, performed via the posterior route under fluoroscopic control.
Retrospective study of 26 patients including 16 (19 injections) with mechanical disorders and ten (16 injections) with inflammatory disorders.
The response rate was 69.3%, the mean pain scale score decrease was 52.3 +/- 40.1%, and the mean duration of pain relief was 8.1 +/- 11.8 months. All three parameters were significantly (P < 0.005) better in the subgroup with inflammatory disorders than in the subgroup with mechanical disorders (response rate, 100% vs 50%; pain scale score decrease, 80 +/- 27% vs 34.2 +/- 40%, and pain relief duration, 16.9 +/- 14.9 months vs 24.5 months). A single patient developed a side effect (moderately severe hypertension).
Glucocorticoid injection into the lateral atlantoaxial joints is a valid treatment alternative in patients who fail to respond to conventional noninvasive therapy.
评估在透视引导下经后路向寰枢外侧关节注射糖皮质激素对各种疾病的总体疗效。
对26例患者进行回顾性研究，其中16例（19次注射）患有机械性疾病，10例（16次注射）患有炎性疾病。
有效率为69.3%，平均疼痛量表评分降低52.3±40.1%，平均疼痛缓解持续时间为8.1±11.8个月。在炎性疾病亚组中，所有这三个参数均显著（P<0.005）优于机械性疾病亚组（有效率分别为100%和50%；疼痛量表评分降低分别为80±27%和34.2±40%，疼痛缓解持续时间分别为16.9±14.9个月和24.5个月）。1例患者出现副作用（中度严重高血压）。
对于对传统非侵入性治疗无反应的患者，向寰枢外侧关节注射糖皮质激素是一种有效的治疗选择。
